ADGRA3

Disease Category: autosomal recessive

Patient Population:

Known Clinical Trials: None known

Check clinicaltrials.gov for updates

Treatment Options: None known

Strategies to Preserve Eye Health:

Institution(s) Conducting Research:

A FACE OF RP

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BRIEF DESCRIPTION

ADGRA3 retinitis pigmentosa is a type of RP caused by mutations in the ADGRA3 gene. ADGRA3 stands for Adhesion G Protein-Coupled Receptor A3. RP is a chronic condition that causes progressive vision loss. Symptoms include difficulty seeing in low light or at night, tunnel vision, or loss of side vision, difficulty adjusting to light changes, difficulty seeing colors, especially blue, and clumsiness due to poor vision. At this time, there is no cure for RP, but medications can help with complications. Genetic testing can help identify the cause of RP, and potentially lead to personalized treatment. (Source: general summary)

Formerly known as GPR125 (Source https://www.deciphergenomics.org/gene/adgra3/overview/clinical-info)

This is for informational purposes only. For medical advice or diagnosis, consult a professional.

IN THE NEWS

Jan 15, 2022

Novel variants in PDE6A and PDE6B genes and its phenotypes in patients with retinitis pigmentosa in Chinese families

Purpose: identify novel variants in PDE6A and PDE6B genes and present its phenotypes in patients with RP in Chinese families.