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Nov 30, 2024
Multigenerational Autosomal Recessive Best Disease
Retinal findings raised suspicion for this inherited retinal disease, confirmed with genetic testing.


Oct 20, 2024
New Gene Therapy for Retinitis Pigmentosa Shows Promise
New research . . . suggests that a new kind of gene therapy can improve vision in people who have lost nearly all sight to RP.

Mar 30, 2024
Progression of PROM1-Associated Retinal Degeneration as Determined by Spectral-Domain Optical Coherence Tomography Over a 24-Month Period
Significant thickness losses could be detected in outer retinal layers by SD-OCT over a 24-month period in patients with PROM1-associated RD


Mar 14, 2024
Gene Therapy Improves Functional Measures in XLRP
Patients with XLRP treated with AGTC-501 gene therapy experienced improvements in visual function including retinal sensitivity . . .


Jul 23, 2022
Potential of endogenous regenerative technology for in situ regenerative medicine
Endogenous regenerative technology involves the use of a patient's biologically active proteins, growth factors and biomaterial scaffolds.

Jun 17, 2022
A new hope for a therapy against retinitis pigmentosa
June 17, 2022 | Université de Genève Journal Reference Olivier Mercey, Corinne Kostic, Eloïse Bertiaux, Alexia Giroud, Yashar Sadian,...


Mar 18, 2022
Antabuse may help revive vision in people with progressive blinding disorders
UC Berkeley researchers have found that a drug once widely used to wean alcoholics off drinking may help improve sight in mice with RD.

Aug 16, 2021
New Treatments for Retinitis Pigmentosa
Existing treatments only help a fraction of the estimated 100,000 Americans with this condition. But advances in gene therapy may soon help.


Jul 13, 2021
CRISPR/Cas9 Gene Editing
X-linked RP caused by RPGR mutations, an attractive target for gene therapy because of its clinical severity and large number of patients.

May 17, 2021
Dissecting the role of EYS in retinal degeneration: clinical and molecular aspects and its implications for future therapy
Ana B. Garcia-Delgado , Lourdes Valdes-Sanchez , Maria Jose Morillo-Sanchez , Beatriz Ponte-Zuñiga , Francisco J. Diaz-Corrales , Berta...


Mar 15, 2021
FDA grants orphan drug designation for RP treatment
The FDA has granted orphan drug designation for chemically induced photoreceptor-like cells to treat retinitis pigmentosa.

Mar 7, 2021
Genome Editing in Retinal Diseases using CRISPR Technology
By: Glenn Yiu, MD, PhD - Department of Ophthalmology & Vision Science, University of California, Davis, Sacramento, California
Ophthalmology

Aug 12, 2020
FDA grants fourth ODD for treatment of PDE6B gene mutation-associated retinal diseases
FDA granted 4th Orphan Drug Designation for novel gene therapy product candidate (OCU400, Ocugen Inc.) in treatment of PDE6B gene mutation.

Jun 10, 2020
New gene therapy technique
Shows promise in stem cell model of retinitis pigmentosa Although the 2017 FDA approval of Spark Therapeutics’ gene therapy Luxturna was...

Jan 31, 2020
CRISPR start, RP first, 50-year case
By Keng Jin Lee and Kanaga Rajan
Published JAN 31, 2020

Jul 15, 2018
Understanding the molecular mechanisms underlying retina degeneration in INPP5E-Joubert Syndrome
Our goal is to identify the onset of degeneration and devise gene-based therapies to ameliorate or cure the retina disease.

Apr 1, 2018
First Gene Therapy FDA-Approved for an Inherited Retinal Disease
In 1972, Friedman and Roblin proposed that it was theoretically possible to introduce “good” DNA to replace defective DNA.


Dec 19, 2017
FDA Approves Gene Therapy for Inherited Blindness Developed by the UPenn and CHOP
In 2017, the FDA approved a gene therapy for RP caused by RPE65. The decision marked the first approved treatment for any form RP.

Jan 27, 2016
Precision Medicine:
Stem cell-derived cell transplantation in the eye is one therapy being explored for inherited retinal degenerations such as RP.


Jun 30, 2013
Stem Cell Therapy: Novel Approach, RP Vision Restoration
Medical Hypothesis, Discovery Innovation Ophthalmology Journal | Harvey Siy Uy, MD, Pik Sha Chan, MD, and Franz Marie Cruz, MD | 2013...
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